Mouse TNR1A-mIgG1-TNF Superfamily -Cambridge Bio

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Mouse TNR1A-mIgG1

Cat No.:    03-04-1412
Product Name:    Mouse TNR1A-mIgG1
Size:    50 μg
Price:    $229

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Cat No.: 03-04-1412
Product Name: Mouse TNR1A-mIgG1
Description: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Type: Protein
Property: P25118 ( aa.22-212)
Source: HEK293
Genbank No.: P25118
Applications: WB,ELISA,Immunogen
Formulation: Each vial contains 50μg purified protein(1mg/ml) in PBS(pH7.4).
Purity: >95%
Storage: Store at -80°C,Avoid freeze / thaw cycle.
Limitation: For research use only,not for use in diagnostic procedures.