Mouse CD14/TLR4-mIgG1(KLH)-CD Moleculars-Cambridge Bio

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Mouse CD14/TLR4-mIgG1(KLH)

Cat No.:    03-01-0207
Product Name:    Mouse CD14/TLR4-mIgG1(KLH)
Size:    50 μg
Price:    $229

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Cat No.: 03-01-0207
Product Name: Mouse CD14/TLR4-mIgG1(KLH)
Description: CD14 serves as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS).CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns such as lipoteichoic acid.CD14 is expressed mainly by macrophages and (at 10-times lesser extent) by neutrophils,which exists as GPI anchored or soluble forms.CD14 mediates the innate immune response to bacterial lipopolysaccharide (LPS), via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Type: Protein
Property: Recombinant Protein
Source: HEK293
Applications: ELISA, WB, Immunogen
Formulation: Each vial contains 50ug purified protein(1mg/ml) in PBS(pH7.4).
Purity: >95%
Storage: Store at -80°C, Avoid freeze / thaw cycle.
Limitation: For research use only, not for use in diagnostic procedures.