Mouse CD11c/CD18(CR4)-CD Moleculars-Cambridge Bio

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Mouse CD11c/CD18(CR4)

Cat No.:    03-01-0230
Product Name:    Mouse CD11c/CD18(CR4)
Size:    50 μg
Price:    $229

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Cat No.: 03-01-0230
Product Name: Mouse CD11c/CD18(CR4)
Description: CD11c,also known as Integrin alpha X (complement component 3 receptor 4 subunit)(ITGAX), forms the heterodimeric integrin alpha-X beta-2(CD18) (αXβ2),comprising a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4).CD11c is found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.Integrin αXβ2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Type: Protein
Property: Recombinant Protein
Source: HEK293
Applications: ELISA, WB, Immunogen
Formulation: Each vial contains 50ug purified protein(1mg/ml) in PBS(pH7.4).
Purity: >95%
Storage: Store at -80°C, Avoid freeze / thaw cycle.
Limitation: For research use only, not for use in diagnostic procedures.