Human CD326(EpCAM)-CD Moleculars-Cambridge Bio

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Human CD326(EpCAM)

Cat No.:    03-01-2144
Product Name:    Human CD326(EpCAM)
Size:    50 μg
Price:    $229

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Cat No.: 03-01-2144
Product Name: Human CD326(EpCAM)
Description: EPCAM acts as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.EpCAM may also play a role in epithelial mesenchymal transition (EMT) in tumors, although its exact effects are poorly understood. Its ability to suppress E-cadherin suggests that EpCAM would promote EMT and tumor metastasis, but its homotypic cell adhesion properties can counteract its ability to suppress E-cadherin.Edrecolomab, catumaxomab and other monoclonal antibodies are designed to bind to it.
Type: Protein
Property: Recombinant Protein
Source: HEK293
Genbank No.: P16422 ( aa.24-265)
Applications: ELISA, WB, Immunogen
Formulation: Each vial contains 50ug purified protein(1mg/ml) in PBS(pH7.4).
Purity: >95%
Storage: Store at -80°C, Avoid freeze / thaw cycle.
Limitation: For research use only, not for use in diagnostic procedures.