Human CD11b/CD18(CR3)-CD Moleculars-Cambridge Bio

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Human CD11b/CD18(CR3)

Cat No.:    03-01-0225
Product Name:    Human CD11b/CD18(CR3)
Size:    50 μg
Price:    $229

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Cat No.: 03-01-0225
Product Name: Human CD11b/CD18(CR3)
Description: CD11b,also called Integrin alpha M (ITGAM),is one protein subunit that forms the heterodimeric integrin alpha-M beta-2(CD18) (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3).αMβ2 is expressed on the surface of many leukocytes involved in the innate immune system, including monocytes, granulocytes, macrophages, and natural killer cells.Integrin αMβ2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Type: Protein
Property: Recombinant Protein
Source: HEK293
Applications: ELISA, WB, Immunogen
Formulation: Each vial contains 50ug purified protein(1mg/ml) in PBS(pH7.4).
Purity: >95%
Storage: Store at -80°C, Avoid freeze / thaw cycle.
Limitation: For research use only, not for use in diagnostic procedures.